The Collegiate Church of St. Nicholas in Guarcino was consecrated in 1760 and is lined with late Baroque decorations.
Inside there are numerous paintings of the 1700s, including a Ranucci, of the school of Cavalier d'Arpino, and some Balbi.
Also, of great artistic importance are the wooden ceiling of the sacristy, the pulpit and the choir of the canons with the episcopal chair.
In the church there is a magnificent pipe organ of 1800 with excellent register, and a statue of the patron Sant'Agnello Abate that is carried in processions celebrating the saint.
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